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| Drug | Use | Note | | :--- | :--- | :--- | | Fluoxetine | Canine compulsive disorder, separation anxiety | 4–6 weeks to onset | | Clomipramine | Canine anxiety, feline urine marking | TCA, more sedating | | Trazodone | Short-term situational anxiety (vet visits, fireworks) | Fast-acting | | Gabapentin | Chronic pain + mild anxiety in cats | Excellent pre-visit | | Selegiline | Canine cognitive dysfunction | MAO-B inhibitor |

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