To run p0sixspwn successfully on a modern PC in 2021+, you need to trick the computer into having the environment p0sixspwn expects.
The requirement for iTunes 10.5 or above has significant implications for users and the jailbreaking community. For users, it means that they need to update their iTunes installation to the latest version, which may not be compatible with their older iOS devices. Additionally, users who are using older versions of Windows or macOS may not be able to update to the latest version of iTunes, which may limit their ability to jailbreak their devices. p0sixspwn requires itunes 105 or above 2021
Newer versions of iTunes lack the specific library hooks p0sixspwn needs. iTunes 11.1.5 (32-bit or 64-bit for older video cards) To run p0sixspwn successfully on a modern PC