No. Microsoft dropped x86 support for server OS starting with Windows Server 2008 R2.
As of 2026, Windows Server 2016 is (ended January 12, 2022) but remains in extended support until January 11, 2027. Extended support means security updates are still provided (for now), but no new features or design changes. The ISO, therefore, is still legal to deploy if you have active Software Assurance or a subscription license—but is it wise? microsoft windows server 2016 iso